ABSTRACT
<p><b>OBJECTIVE</b>To explore the effect of warming needling pretreatment for endometrial receptivity before frozen-thawed embryo transfer (FET).</p><p><b>METHODS</b>Fifty-six repeatedly embryo transfer (ET) failure patients with ultrasound showing follicular phase endometrium of C type, hysteroscopy examination presenting endometritis were randomly assigned into an observation group (25 cases) and a control group (31 cases). The patients in the observation group three months before ET were treated with antibiotics in the menstrual period, warming needle (once a day) at Zhongwan (CV 12), Tianshu (ST 25), Guanyuan (CV 4), Zhongji (CV 3), Zigong (EX-CA 1), Liangu (ST 34), Zusanli (ST 36), Shangjuxu (ST 37), Xiajuxu (ST 39) after menstruation until the ovulation stopped, and oral administration of progesterone was applied after ovulation. The patients in the control group three months before ET were treated with antibiotics in the menstrual period, and oral administration of progesterone was applied after ovulation. Continuous three menstrual periods were carried out for the both groups. The changes of endometrial thickness, type and endometrial blood flow and the outcome of FET were observed.</p><p><b>RESULTS</b>Endometrial morphology and blood flow were improved after treatment in the two groups (all<0.01), with better results in the observation group (both<0.01). The embryo transplantation rate and pregnancy rate in the observation group were higher than those in the control group (both<0.01), and the early abortion rate decreased (<0.01).</p><p><b>CONCLUSIONS</b>Warm needling may improve endometrial receptivity, embryo transplantation rate and pregnancy rate and decrease early abortion rate by regulating endometrial morphology and blood flow.</p>
ABSTRACT
In 1982, ADP-ribosylation factors (ARFs), a family of GTP-binding proteins associated with Golgi complexes, were initially recognized based on their ability to stimulate the ADP-ribosyltransferase activity of cholera toxin in vitro, and named so. In fact, this pathophysiologic activity has been useful for functionally defining members of the ARF family. However, during last decade, genetic and biochemical studies have shown the physiologic role of ARFs that also play an essential role in intracellular vesicular transport, particularly in Golgi complexes, activate phospholipase D activity as a nod of signal transduction of cells. Moreover, their more functions were revealed continuously recently. Especially, human ARF1 was found earliest, and studied profoundly in human body cell. Therefore, in this article, there is a comprehensive review about its regulators and effectors, functions and its possibilities involved in tumorigenesis, development of tumors.
ABSTRACT
Objective To explore the ultrasonic imaging and clinic characteristics to improve the diagnosis on sacrococcygeal teratoma(SCT).Methods Ultrasonic,clinical and pathological characteristics of 49 SCT cases were analyzed retrospectively.Results SCT occurred commonly in young children under age 7,especially in neonates and infants. 87.8% cases were benign,others were malignant.The ultrasonic characteristics in SCT were special.Conclusions Ultrasound is the first choice to diagnose SCT.